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Updated: Jan 7, 2026

An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity
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An Efficient Method for the Synthesis of Peptoids with Mixed Lysine-type/Arginine-type Monomers and Evaluation of Their Anti-leishmanial Activity

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丁甲基化素作为强烈的利什曼杀伤剂:设计,合成和结构-活性关系

Renan Augusto Gomes1, Leonardo Luiz Gomes Ferreira2, Witor Ribeiro Ferraz1

  • 1LITEC, Department of Pharmacy, School of Pharmaceutical Science, University of São Paulo, 05508-9000, Brazil.

Bioorganic & medicinal chemistry letters
|December 26, 2025
PubMed
概括

新型肉甲基酸对莱什曼病和查加斯病寄生虫表现出强烈的活性. 这些化合物为开发有效治疗被忽视的热带疾病提供了一个有希望的新支架.

关键词:
辛纳米尔阿里尔化.计算化学是一种计算化学.莱什曼尼亚的捐赠人基于干的药物设计.热带被忽视的疾病

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