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Updated: Jan 7, 2026

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox
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基于生理学的多二-153的药理动力学建模:跨物种推断和人类暴露模拟

Ji-Hun Jang1, Seung-Hyun Jeong2,3

  • 1College of Pharmacy, Chonnam National University, 77 Yongbong-Ro, Buk-Gu, Gwangju, 61186, Republic of Korea.

Archives of toxicology
|December 26, 2025
PubMed
概括

聚二-153 (PCB-153) 在人体脂肪组织中积累. 一个新的基于生理学的药理动力学 (PBPK) 模型预测了PCB-153的组织积累,改善了对持久性有机污染物的人类风险评估.

关键词:
跨种特异推算 跨种特异推算基于生理学的药物动力学模型.多化双-153的使用情况.参考剂量是指参考剂量.风险评估 风险评估 风险评估组织分布 组织分布

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