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Updated: Jan 7, 2026

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有针对性的蛋白质降解:物种,疾病和有效利用

Tian Yue1, Jian He1,2, Jun Hou3

  • 1Department of Cardiology, Chengdu Institute of Cardiovascular Disease, The Third People's Hospital of Chengdu/Affiliated Hospital of Southwest Jiaotong University, Chengdu, Sichuan, 610031, China.

Journal of translational medicine
|December 26, 2025
PubMed
概括

有针对性的蛋白质降解 (TPD) 通过清除有害蛋白质来治疗疾病的新方法. 本综述探讨了TPD策略和药物输送系统,以提高治疗疗效和临床转化.

关键词:
癌症 癌症 癌症 癌症纳米颗粒 纳米颗粒神经退行性疾病的神经退行性疾病这就是PROTAC.有针对性的蛋白质降解降解.

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