在日本2型糖尿病患者中,膀过活的患病率和相关因素
Hiroyuki Ito1, Erika Watanabe2,3, Mari Tanaka2,4
1Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital, Tokyo, Japan.
Geriatrics & gerontology international
|December 27, 2025
概括
过度活跃的膀 (OAB) 影响了24%的日本老年人患有2型糖尿病. -葡萄糖共运输体2 (SGLT2) 抑制剂的使用与OAB有关,突出显示了糖尿病患者需要监测尿路症状的必要性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
- 老年病的医生 老年病的医生
背景情况:
- 过度活性膀 (OAB) 是一种常见的疾病,影响糖尿病患者的生活质量.
- 目前尚不清楚OAB的患病率及其与糖尿病药物的相关性.
研究的目的:
- 为了确定日本2型糖尿病患者中OAB的患病率.
- 为了确定与OAB相关的因素在这个人群中,包括抗糖尿病药物.
主要方法:
- 一项涉及289名55岁以上2型糖尿病门诊患者的横截面研究.
- 使用过度活性膀症状评分 (OABSS) 进行评估.
- 后勤回归确定了与OAB相关的因素.
主要成果:
- 在OAB的患病率为24%.
- 糖尿病持续时间较长,脑血管疾病史和SGLT2抑制剂使用与OAB有关.
- 没有发现与HbA1c或外围神经病变的相关性;只有32%的OAB患者接受了治疗.
结论:
- 在患有2型糖尿病的老年人中,OAB很常见.
- SGLT2 抑制剂可能会增加OAB风险.
- 建议在选择治疗时积极监测和考虑OAB,以保持生活质量.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
4.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.2K
Diabetes: Symptoms, Diagnosis, and Complications
2.0K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.0K
Diabetes Mellitus: Overview and Type I Subtype
4.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.8K
Carbohydrate Metabolism
13.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
13.7K
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
346
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
346
Pathophysiology of Diabetes
3.1K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.1K


