应用Noise2Inverse和适应 (Noise2Phase) 于单面膜X射线相对比微计算机断层扫描
Khushal Shah1, Grammatiki Lioliou1, Dai Chen1,2
1Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
Journal of microscopy
|December 27, 2025
概括
深度学习无声化显著减少了单面罩边缘照明X射线曝光时间的X射线相位对比微型CT. 这种技术,Noise2Inverse,使材料的3D成像速度更快,即使噪音水平高.
科学领域:
- 医疗成像医学成像
- 材料科学 材料科学 材料科学
- 计算成像技术的成像
背景情况:
- X射线相位对比成像 (XPCI) 提供使用微计算机断层扫描 (micro-CT) 的材料的高对比度3D可视化.
- 单面罩边缘照明方法增强了对比度,但由于减少了X射线流量,需要更长的曝光时间.
研究的目的:
- 调查基于深度学习的denoising的应用,以缓解XPCI微CT中的曝光时间需求.
- 在这种成像模式下,评估Noise2Inverse技术在严重噪音条件下的性能.
主要方法:
- 将Noise2Inverse深度学习消噪算法集成到XPCI微CT图像处理工作流中.
- 开发了一种适应的算法,Noise2Phase,适合XPCI边缘照明的特定特征,避免投影分裂.
主要成果:
- 证明了Noise2Inverse的适用性和有效性,用于单面膜边缘照明XPCI微CT.
- 展示了成功的降噪,可以缩短曝光时间和更快的3D成像.
- 验证了Noise2Phase的性能,这是一种适合该特定XPCI技术的深度学习方法.
结论:
- 深度学习无声化,特别是Noise2Inverse及其适应Noise2Phase,可以显著减轻XPCI微CT的长时间暴露时间限制.
- 这些先进的图像处理技术促进了更快,更有效的高对比度3D材料成像.
- 这些发现为在材料科学研究中更广泛采用XPCI微CT铺平了道路.
相关概念视频
Phase Contrast and Differential Interference Contrast Microscopy
11.9K
Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
11.9K
Computed Tomography
7.9K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
7.9K
Imaging Studies III: Computed Tomography
251
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
251


