对希尔施普朗格病的Soave与斯文森程序的比较疗效:系统性审查和元分析
Zhihua Ma1, Jie Tang1, Nan Xie2
1Department of neonatal surgery, Childre's Hospital of Nanjing Medical University, Nanjing, 210008, China.
Pediatric surgery international
|December 27, 2025
概括
与Soave手术相比,斯文森手术治疗赫施普隆病 (HSCR) 的手术效率提高,便秘减少. 推个性化手术选择,需要进一步的多中心研究,以获得最佳的长期HSCR结果.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床证据综合研究
背景情况:
- 赫施普隆病 (HSCR) 是一种需要手术干预的先天性疾病.
- 索维和斯文森手术是HSCR的常见手术方法.
- 这些程序的比较疗效数据对于手术决策至关重要.
研究的目的:
- 进行一项元分析,比较Soave和Swenson程序对HSCR的疗效.
- 为选择HSCR最佳手术方法提供基于证据的支持.
主要方法:
- 在中国和英语数据库中进行系统的文献搜索.
- 包括11项涉及972名儿童的回顾性队列研究.
- 使用Review Manager 5.4.1和Stata 17.0进行元分析,以比较外科手术期间的参数,并发症和肠功能.
主要成果:
- 与Soave相比,斯文森手术与更短的手术时间,减少血液损失和更短的住院时间有关.
- 斯温森手术显示,手术后便秘的统计显著减少.
- 在两种手术之间没有观察到早期并发症,希尔施普朗相关肠球炎 (HAEC) 或尿液保留的显著差异.
结论:
- 在HSCR处理中,Soave和Swenson程序都有明显的优势.
- 斯温森手术提高了手术效率,并降低了便秘率.
- 采程序提供了更清晰的解剖平面,可能降低神经损伤风险;建议进行个性化选择和前性研究.
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