从不同环境中招募的主观认知衰退患者的记忆测试表现:系统性审查和元分析
Katie A Peterson1, Adrian Leddy1, Fiona Ellis1
1Department of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, Norwich, UK.
Neuropsychology review
|December 27, 2025
概括
主观认知衰退 (SCD) 可能表明早期的神经退行,与健康个体相比显示微妙的记忆障碍. 需要进一步的研究来澄清这些记忆差异的临床意义.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 老年学是一门学科.
背景情况:
- 主观认知衰退 (SCD) 是自我报告的认知障碍,没有客观缺陷.
- SCD可能代表神经退行最早的阶段.
- 了解SCD中的记忆性能对于早期检测至关重要.
研究的目的:
- 为了确定客观记忆表现是否在SCD和没有SCD的个体之间有所不同.
- 为了比较SCD和轻度认知障碍 (MCI) 组之间的记忆性能.
- 综合现有关于SCD记忆缺陷的证据.
主要方法:
- 在多个数据库中进行系统的文献搜索 (20142023).
- 情节性记忆任务执行的随机效应元分析.
- 包括从社区/医疗环境中招募SCD的研究.
- 单独的SCD与MCI比较的元分析.
主要成果:
- 与非SCD对照组相比,患有SCD的个体的记忆表现明显差 (赫奇斯的g = -0.19).
- 患有SCD的个体表现明显好于MCI参与者 (赫奇斯的g = 1.20).
- 发现了显著的异质性和出版偏差的风险.
结论:
- 详细的记忆评估可以检测到SCD中微妙的客观记忆障碍.
- 在SCD中观察到的小效应大小的临床意义需要进一步调查.
- 需要更高质量,更大规模的研究来探索缓和因素.
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