相关实验视频

Updated: Jul 10, 2026

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling
21:55

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling

Published on: April 2, 2012

29.1K

在与驼类连接体的亲和性捕获中对全 AAV 囊体的选择性

Lukas Bongers1, Linda E Franken2, Dominik Hoch1

  • 1Gene Therapy Technical Research & Development, Roche Diagnostics GmbH, 82377 Penzberg, Germany.

Journal of chromatography. A
|December 27, 2025
PubMed
概括

一种新的亲和力捕获方法增强了腺相关病毒载体 (AAV) 的净化. 这种方法显著丰富了全AAV囊体,提高了基因治疗应用下游处理的效率.

关键词:
腺相关病毒的病毒.亲和色谱法是一种亲和色谱法.卡梅利德的亲缘关系连接物.完全封闭选择性的选择性基因治疗是一种基因疗法.

更多相关视频

Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus AAV Capsid Variants09:20

Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus AAV Capsid Variants

Published on: October 18, 2022

5.1K
Author Spotlight: Improved Method for Production and Purification of Adeno-Associated Viral Vectors09:12

Author Spotlight: Improved Method for Production and Purification of Adeno-Associated Viral Vectors

Published on: April 5, 2024

4.3K

相关概念视频

Affinity Chromatography01:03

Affinity Chromatography

Affinity chromatography is a powerful technique extensively utilized for separating and purifying specific biomolecules from complex mixtures. It capitalizes on the highly selective binding between an analyte and its counterpart, such as antibody-antigen interactions. The counterpart is immobilized on the stationary phase, forming an affinity column. The stationary phase typically consists of solid support, such as agarose or porous glass beads, immobilizing the affinity ligand. The mobile...