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Updated: Jan 7, 2026

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
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Published on: May 2, 2025

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作为PD-L1抑制剂的环金属化复合物:通过COX-2阻断抑制表达

Yating Zhang1, Jingyue Zhao1, Zhengqi Shen1

  • 1Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.

Journal of inorganic biochemistry
|December 27, 2025
PubMed
概括

这项研究引入了一种新型的复合物,Ir-FA,作为编程细胞死亡1 (PD-L1) 的基于金属的抑制剂. 艾尔-FA选择性地向癌细胞,减少炎症,并降低PD-L1的调节,为癌症免疫治疗提供了一种新的策略.

关键词:
在COX-2阻塞中.循环金属化与的关系免疫治疗是一种免疫疗法.抑制PD-L1的发生.瘤选择性 瘤选择性

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