在结构调节的纤维素丝中Ag-ZnO纳米颗粒的协同作用使抗菌效率高,细胞毒性低
Yiyan Jiang1, Hongkuo Si1, Maolin Chen1
1School of Materials Science and Engineering and Institute of Composite Materials, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
International journal of biological macromolecules
|December 27, 2025
概括
研究人员开发了一种新的方法,用于制造抗微生物纤维素丝,使用现场合成银和氧化物纳米颗粒. 这些细丝显示出高的杀菌率对大肠杆菌和金黄色细菌与低细胞毒性.
科学领域:
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
- 纳米技术纳米技术
背景情况:
- 通过湿直接制造抗菌纤维素纤维丝受到纳米粒子合成和分散方面的挑战的阻碍.
- 现有的方法往往涉及复杂的程序,以创建有效的抗微生物材料.
研究的目的:
- 为制造抗微生物再生纤维素丝开发一种简化的一现场合成策略.
- 研究含有银纳米颗粒 (AgNP) 和/或氧化 (ZnO) 颗粒的纤维素丝的结构和抗菌特性.
主要方法:
- 在性纤维素溶解系统中采用了一位合成方法.
- 抗菌颗粒 (Ag NPs,ZnO) 在纤维素链上在现场形成.
- 通过调节颗粒组成和凝固浴,生产了三种类型的纤维:ACF (Ag NPs),ZCF (ZnO) 和AZCF (Ag NPs和ZnO).
主要成果:
- 由于Ag NPs和ZnO之间的协同相互作用,AZCF线丝表现出光滑的表面,密集,均的纳米粒子分布.
- ACF显示表面光滑,Ag NP可见度有限,而ZCF显示表面粗度来自ZnO聚合.
- 所有制造的细菌丝都显示出高的抗菌活性 (>95%的杀菌率对大肠杆菌和金黄色细菌) 和低的细胞毒性.
结论:
- 在现场开发的合成策略有效地产生了结构上独特的抗微生物再生纤维素丝.
- 细丝的抗菌效果源于一种协同作用,包括活性氧物种 (ROS) 生产和受控的金属离子释放.
- 这种方法为制造具有可调节性质的先进抗微生物纤维素基材料提供了一个有前途的途径.
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