在慢性胰腺炎中使用大麻:叙述性审查
Darius J Javidi1, Timothy B Gardner1
1Center for Digestive Heath, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
概括
在慢性胰腺炎患者中,大麻的使用正在增加,一些研究表明减少了阿片类药物的使用. 然而,大麻的证据.
科学领域:
- 胃肠病学和疼痛管理
背景情况:
- 慢性胰腺炎经常导致衰弱的疼痛,需要新的治疗策略.
- 目前慢性胰腺炎疼痛的治疗选择有限,往往不足.
研究的目的:
- 审查有关大麻及其衍生品在治疗慢性胰腺炎疼痛方面的有效性和安全性的现有证据.
主要方法:
- 对调查慢性胰腺炎患者大麻使用的研究进行叙述性综述.
主要成果:
- 在这个人群中,大麻的使用正在增加,特别是在长期使用阿片类药物的年轻男性中.
- 一项研究表明,医用大麻减少了阿片类药物消费,而另一项研究发现,THC对缓解疼痛无效.
- 有限,低质量的证据表明,在住院患者中存在潜在的益处.
结论:
- 目前关于大麻治疗慢性胰腺炎的证据基础稀疏且质量不佳.
- 进一步严格的研究是必要的,以确定医用大麻的治疗潜力慢性胰腺炎.
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