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通过触发PGK1乙化,PRAS40通过增强糖解来促进结直肠癌的干细胞生长

Chengfei Zhang1, Yufei Bo1, Ting Zhang1,2

  • 1Department of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, 9 South Lvshun Road, Dalian, Liaoning, 116044, China.

Oncogenesis
|December 27, 2025
PubMed
概括

富含林的Akt基质40 (PRAS40) 通过PRAS40/PGK1轴促进糖解,驱动结直肠癌干. 抑制这种途径为结直肠癌治疗提供了潜在的治疗策略.

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