来自Ferula communis的生物灵感银纳米颗粒的结构分析和抗菌评估
Yasmeen M G Alshamari1,2, Hamad Z Alkhathlan3, Ponmurugan Karuppiah4
1Department of Chemistry, Faculty of Science, King Abdulaziz University, P.O Box 80200, Jeddah, 21589, Saudi Arabia.
Scientific reports
|December 27, 2025
概括
使用 Ferula communis 提取物进行银纳米粒子 (AgNPs) 的绿色合成是环保且具有成本效益的. 合成的AgNP对各种细菌和真菌菌株表现出显著的抗菌活性,由植物化学物质增强.
科学领域:
- 绿色化学和纳米技术
- 生物技术和微生物学
背景情况:
- 传统的纳米粒子合成方法带来环境和健康风险.
- 使用植物提取物的绿色合成提供了一种可持续的,无毒的,经济高效的替代方案.
- Ferula communis提取物被探索为纳米颗粒制造的新型减少剂.
研究的目的:
- 使用 Ferula communis 提取物合成银纳米粒子 (AgNPs).
- 描述合成的AgNP,并确定参与合成的关键植物化学物质.
- 评估合成的AgNP对各种病原体的抗菌疗效.
主要方法:
- 使用Ferula communis叶片提取物进行AgNPs的绿色合成.
- 使用各种分析技术 (例如GC-MS) 进行AgNP的表征.
- 对细菌 (黄金葡萄球菌,大肠杆菌, Pseudomonas aeruginosa, Klebsiella pneumoniae, Bacillus subtilis) 和真菌 (Candida albicans, Aspergillus niger) 菌株进行抗菌活性测试.
主要成果:
- 通过使用Ferula communis提取物作为减少剂,成功合成了晶体,球形的AgNP.
- 在GC-MS分析中,提取物中发现了67种化合物,其中stigmasterol和pentadecanoic酸占主导地位.
- 合成的AgNP表现出显著的广泛抗菌活性,超过单独的植物提取物.
结论:
- 费鲁拉共产的提取物是一种有效的绿色降解剂,用于AgNP合成.
- 合成的AgNP具有强大的抗微生物特性,可能是由于与植物化学物质的协同作用.
- 这种绿色合成方法为开发新型抗菌剂提供了一个有前途的途径.
更多相关视频
11:19Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
Published on: May 10, 2018
10.6K
08:08Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
22.7K
相关概念视频
01:28Antimicrobial Effectiveness
876
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
876
01:23Antimicrobial Proteins
12.9K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
12.9K