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Updated: Jan 7, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation
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同变量调整的剂量反应曲线与疫苗临床试验的应用

Nong Shang1, Stephanie Schrag1, Rebecca Kahn1

  • 1Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Journal of biopharmaceutical statistics
|December 28, 2025
PubMed
概括

这项研究引入了共变调整逻辑模型 (CALM),以准确地从观察数据中确定剂量-反应关系,即使采用混和偏差采样. CALM改善了疫苗有效性研究的因果推断.

关键词:
观察性研究是指观察性研究.因果风险比率因果风险比率剂量-反应曲线疫苗的有效性 疫苗的有效性

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