失调的情绪干扰处理在情感和认知控制大脑区域在失眠障碍失眠障碍
Shuo Wang1, Yun Tian2, Linzhe Zhong3
1Sleep and NeuroImaging Center, Faculty of Psychology, Southwest University, Chongqing, 400715, China; Key Laboratory of Cognition and Personality, Southwest University, Ministry of Education, Chongqing, 400715, China.
Sleep medicine
|December 28, 2025
概括
失眠障碍患者在情绪干扰任务中表现出大脑活动变化和反应时间减慢. 这些患者的睡眠障碍与减少尾状核失活有关,影响情绪调节.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 失眠障碍 (ID) 的特点是严重的睡眠障碍.
- 认知和情绪失调在ID中很常见.
- 了解ID中情绪干扰的神经支柱至关重要.
研究的目的:
- 研究ID患者在情绪干扰期间的行为和神经反应.
- 检查睡眠障碍与智障患者的认知情绪控制之间的关联.
- 为了比较ID患者和健康对照 (HC) 的情绪干扰处理.
主要方法:
- 43名ID患者和43名HC患者在情绪干扰任务 (EIT) 中接受了功能磁共振成像 (fMRI).
- 使用ANOVA分析行为数据 (反应时间,准确性) 和大脑激活.
- 通过自我报告问卷来评估睡眠障碍,并通过相关性来探索其与大脑活动的联系.
主要成果:
- 与HC相比,ID患者表现出较慢的反应时间和较低的准确性,特别是在处理情绪刺激时.
- 在EIT期间,fMRI揭示了ID患者右背侧前额皮层 (DLPFC) 和尾状核的活性变化.
- 在ID患者中,更大的睡眠障碍与在忽视恐惧刺激时减少右尾状核失活相关.
结论:
- 在前额叶皮质控制和情绪突出性的条形处理中,注意力依赖的变化在ID中很明显.
- 这些发现表明,在失眠障碍中,睡眠障碍与认知情绪调节受损之间存在联系.
- 这项研究强调了智商对情绪干扰和调节的神经机制的影响.
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