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在跨导管大动脉置换手术期间,两种镇静方案之间的随机临床试验:胺和普罗波福尔与雷米芬坦尼尔和德克斯梅托米丁相比

Anna Castellari1, Matteo Lucchelli1, Mattia Gomarasca1

  • 1S.C. Rianimazione e Anestesia Legnano, ASST Ovest Milanese, Legnano, Italy.

Journal of clinical anesthesia
|December 28, 2025
PubMed
概括

与Remifentanil和Dexmedetomidine (REMIDEX) 相比,胺和普罗波 (KETOFOL) 镇静方案在跨导管大动脉置换 (TAVR) 期间表现出更好的稳定性和更少的呼吸问题. 雷米德克斯与增加的呼吸系统酸化和更长的诱导时间有关.

关键词:
德克斯梅德德托米丁的使用方法胺基氨酸 (ketamine) 是一种可以在Ketofol的Ketofol中使用.程序性镇静 程序性镇静普罗波福尔 (Propofol) 是一种雷米德克斯 (Remidex) 是一个药物.在Remifentanil中使用Remifentanil.通过导管更换大动脉门

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Parenteral Anesthetics: Overview01:24

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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