关于环境温度对人类不孕症的影响的范围审查
Seulkee Heo1, Garam Byun1, Yongsoo Choi1
1School of the Environment, Yale University, New Haven, CT, 06511, USA.
Environmental research
|December 28, 2025
概括
较高的环境温度会对男性生育能力产生负面影响,减少精子参数,增加不育率. 本综述对温度和人类生育能力的研究进行了绘制,确定了公共卫生方面的知识差距.
科学领域:
- 环境健康 环境健康
- 生殖流行病学 生殖流行病学
- 人类生育能力研究 研究人类生育能力
背景情况:
- 环境温度是影响哺乳动物雌性体生产的已知因素.
- 人们对与环境温度相关的人类生殖结果越来越感兴趣,但系统的证据合成有限.
- 绘制与环境温度有关的人类不孕症结果对公共卫生和识别研究差距至关重要.
研究的目的:
- 系统地审查和绘制有关环境温度和人类生育能力的流行病学研究.
- 确定现有研究中检查的温度指标和生殖结果的类型.
- 突出该领域的方法限制和知识差距.
主要方法:
- 在文献数据库中进行系统搜索,得出21,332个初始记录.
- 包括135个符合条件的温度和人类生育能力的流行病学研究.
- 温度暴露指标的分类 (例如,环境温度,热量指数,极热) 和生殖结果 (例如,精子参数,ART结果,不孕症诊断).
主要成果:
- 在不同地理区域确定了七种类型的生殖结果.
- 较高的温度暴露始终与精子参数的减少 (例如,运动能力) 和不孕不育的可能性增加有关.
- 其他结果类型表现出异质的暴露-反应关联,使用不同的方法和研究设计.
结论:
- 研究始终将更高的环境温度与对男性生殖健康的不利影响和不孕症的增加联系在一起.
- 方法上的局限性很普遍,包括缺乏纵向设计和详细的暴露评估.
- 未来的研究应该专注于强大的方法论,以告知公众健康和临床决策有关温度和生育能力.
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