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Updated: Jan 7, 2026

Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury
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Standardized Colon Ascendens Stent Peritonitis in Rats - a Simple, Feasible Animal Model to Induce Septic Acute Kidney Injury

Published on: February 15, 2022

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一个临床前随机的控制剂量优化大剂量甲酸,用于逆转格拉姆阴性败血症引起的心血管,大脑和功能障碍

Connie Pei Chen Ow1, Rachel M Peiris1, Anton Trask-Marino1

  • 1Translational Cardiovascular and Renal Research Group and Preclinical Critical Care Unit, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 30 Royal Parade, Parkville, 3052, Melbourne, VIC, Australia.

Critical care (London, England)
|December 28, 2025
PubMed
概括

高剂量的酸 (3.0 g/kg) 有效地逆转了羊的败血症引起的心血管和功能障碍. 这一剂量达到~10 mmol/L的血度,这对于格兰阴性败血症的多器官保护至关重要.

关键词:
急性损伤是什么?急性损伤是什么?氧气过低是因为缺氧.缺血 缺血是因为缺血.一个巨剂量的大剂量.败血症 这是一种败血症.亚酸盐是什么? 亚酸盐是什么?血管压缩器是一种压缩器.

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