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Updated: Jul 26, 2026

Intracerebroventricular Viral Injection of the Neonatal Mouse Brain for Persistent and Widespread Neuronal Transduction
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马赛克AAV在中枢神经系统和外围神经系统中调解有效的转导

Min Jiang1, Wenqing Yin1, Xiaolu Mo1

  • 1Key Laboratory of Organ Development and Regeneration of Zhejiang Province, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, 311121, People's Republic Of China.

Molecular brain
|December 28, 2025
PubMed
概括

研究人员开发了一种新的马赛克腺相关病毒 (AAV) 载体,AAV-PHP. (S+eB),有效地针对中枢神经系统 (CNS) 和外周神经系统 (PNS) 进行基因治疗. 这种双重向向量通过减少肝脏转导来提高安全性.

关键词:
在AAV-PHP.SS中使用.在 AAV-PHP.eB 中.在CNS中,CNS是CNS.在PNS中,PNS是PNS.

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