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Updated: Jan 7, 2026

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation
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MKRN1 通过 Akt 和 AMPK 路径调节 RANKL 诱导的差异化

Inyoung Kim1,2, Jung Ha Kim1, Kabsun Kim1

  • 1Department of Pharmacology, Chonnam National University Medical School, Gwangju, Republic of Korea.

Journal of cellular physiology
|December 29, 2025
PubMed
概括

马科林环指蛋白1 (MKRN1) 通过调节Akt和AMP激活蛋白激酶 (AMPK) 信号,促进骨质细胞分化. 缺乏MKRN1会增加骨体积,这表明它对骨疾病的治疗潜力.

关键词:
这就是AMPKK.标签: 活动 活动 活动一个MKRN1一个MKRN1骨质细胞分化的分化.

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