对阿片类药物使用障碍手术患者的布普伦诺芬和甲处方的地理差异
Caitlin P Coates1, Margaret McGlothlin Carroll2,3, Janelle M Richard2
1University of New England College of Osteopathic Medicine, 11 Hills Beach Rd, Biddeford, ME 04005, United States.
Drug and alcohol dependence reports
|December 29, 2025
概括
对阿片类药物使用障碍 (MOUD) 的药物,特别是布普伦诺芬,越来越多地被处方给缅因州的手术患者. 这一趋势表明,人们正在远离甲,特别是在农村地区,这影响了阿片类药物使用障碍的治疗.
科学领域:
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
- 手术护理 手术护理
背景情况:
- 阿片类药物使用障碍 (OUD) 患者在服用阿片类药物使用障碍 (MOUD) 药物时经常需要手术.
- 缅因州是一个以农村为主的州,面临着严重的阿片类药物危机,使MOUD在手术患者中的使用成为一个关键的公共卫生问题.
研究的目的:
- 评估梅恩州城市和农村卫生系统中OUD手术患者中MOUD使用的趋势.
- 在这个患者群体中,通过时间和地理位置来比较布普伦诺芬与甲的使用情况.
主要方法:
- 对接受MOUD手术前治疗的OUD入院MaineHealth医院 (2014-2023) 的成年外科患者的回顾性分析.
- 数据收集包括人口统计,临床特征和农村-城市指定.
- 主要结局:甲与布普伦诺芬使用的时间趋势;使用基平方测试进行统计比较.
主要成果:
- 在MOUD的2099名手术患者中,71.4%接受了布普伦诺芬,28.6%接受了美沙.
- 农村患者比城市患者 (68.5%) 更容易接受布普伦诺芬 (75.1%).
- 从2014年到2023年,在农村和城市地区,布普伦诺啡的处方量显著增加,甲使用量相应下降.
结论:
- 在缅因州的农村和城市人口中,在手术患者的MOUD中,对布普伦诺芬而不是甲的显著转变被观察到.
- 虽然这两种MOUD都安全用于外科手术,但管理协议需要标准化.
- 进一步的研究对于了解这些处方趋势的临床影响和确保OUD患者的护理连续性至关重要.
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