尿病的全球患病率:对方法异质性进行的元分析
Víctor Juan Vera-Ponce1, Nataly Mayely Sanchez-Tamay1, Jhosmer Ballena-Caicedo1
1Facultad de Medicina (FAMED), Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM), Chachapoyas, Peru.
Frontiers in urology
|December 29, 2025
概括
尿病影响全球近11%,这是一个重大的公共卫生问题. 诊断工具和抽样等方法学因素显著影响流行率估计,强调需要标准化.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 尿病 (结石) 是一个日益严重的全球健康问题.
- 了解其真正的流行率对于公共卫生战略至关重要.
研究的目的:
- 通过系统性审查和元分析估计尿病的全球患病率.
- 确定有助于流行异质性的方法因素.
主要方法:
- 按照PRISMA指南进行系统审查,搜索主要数据库.
- 来自22项观察性研究 (1,276,826名参与者) 的比例的元分析.
- 根据诊断方法 (超声波,CT,自我报告),性别,采样和地区进行子组分析.
主要成果:
- 全球尿病患病率估计为10.85%,具有显著的异质性 (I2=100%).
- 患病率因诊断方法而异 (自我报告最高为13.28%,CT最低为7.83%).
- 男性 (12.93%) 与女性 (8.91%) 的患病率更高;注意到区域差异 (非洲22.3%,北美8.3%).
结论:
- 尿病影响全球约11%的人口,构成重大公共卫生挑战.
- 方法的变化,特别是诊断方法和采样,解释了许多观察到的异质性.
- 标准化诊断和招聘标准对于准确的流行率测量和明智的卫生政策至关重要.
相关概念视频
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
346
Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
346
Urinary Tract Calculi III: Medical Management
170
The diagnosis of renal calculi involves several imaging techniques, including non-contrast CT scans and ultrasound. These methods help visualize kidney stones, assess their size and location, and detect possible obstructions. Additionally, Measuring urine pH is useful for diagnosing specific stone types, such as struvite (alkaline pH) and uric acid stones (acidic pH). Cystine stones are primarily linked to cystinuria, a genetic condition. A urinalysis helps detect blood in the urine (hematuria)...
170
Urinary Tract Calculi I: Introduction
375
Renal calculi, or kidney stones, are solid deposits of minerals and salts formed inside the kidneys. In medical terminology, "calculus" refers to the stone itself, while "lithiasis" describes the process of stone formation. Depending on their location within the urinary system, these stones may be classified as either urolithiasis, when situated within the urinary tract, or nephrolithiasis, when located within the kidneys. Each term signifies the specific impact of the stone.Predisposition...
375
Urinary Tract Calculi VI: Surgical Management
328
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
328
Urinary Tract Calculi IV: Nutrition Therapy and Prevention
338
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
338
Urinary Tract Calculi V: Nursing Management
253
AssessmentSubjective Data: Obtain a detailed health history, including any recent or chronic urinary tract infections, periods of immobilization, previous episodes of renal calculi, and medical conditions such as gout, benign prostatic hyperplasia, or hyperparathyroidism. Review the medication history for drugs that may influence stone formation, including allopurinol, analgesics, loop diuretics, or thiazide diuretics. Document the use of long-term indwelling catheters and any past surgical...
253


