在登革热感染中爆发性肝衰竭:苏丹资源有限的疫情中两名幸存者
Mohamed Bushra Alajab1, Sawsan Ahmed Omer Elameen1, Fatima Abdelmonem Yousif Mohamed1
1Faculty of Medicine University of Gezira Wad Madani Sudan.
Clinical case reports
|December 29, 2025
概括
即使在资源有限的环境中,早期识别和支持性护理,包括N-乙半氨酸,对于治疗严重的登革热相关的发性肝功能衰竭至关重要. 这两位患者都完全康复了.
科学领域:
- 医学 医学 医学 医学 医学
- 肝病学 肝病学是一种肝病学.
- 传染性疾病 传染性疾病
背景情况:
- 登革热病毒感染是一个重大的全球健康问题,经常导致轻微的肝脏干扰.
- 发性肝衰竭 (FHF) 是登革热的罕见但危及生命的并发症,需要快速诊断和管理,特别是在资源有限的地区.
研究的目的:
- 在苏丹男性中报告两例登革热相关的FHF病例.
- 强调迅速识别和密集的支持性管理对改善结果的重要性.
主要方法:
- 两名男性患者的病例报告呈现FHF症状,包括黄,肝酶升高,肝脏脑病和凝血病.
- 治疗包括支持性护理,N-乙半氨酸,凝血病的纠正,葡萄糖输液和脏替代疗法为一名患者.
主要成果:
- 两名患者都呈现出严重的登革热相关的FHF和肝脑病变; 一名患者同时患有乙型肝炎和急性损伤.
- 在两种情况下,密集的支持性管理导致了渐进的临床和生化改善.
- 在随访期间观察到肝脏和功能完全恢复.
结论:
- 登革热相关的FHF虽然严重,但通过早期识别和全面的支持性护理,可以成功管理.
- N-乙半氨酸和密集的支持措施对于登革热引起的FHF的生存至关重要,即使在资源有限的环境中也是如此.
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