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催素诱导的视觉突出处理的调制

Stephanie Muller^1,2, Federico Cavanna^1,2, Laura Alethia de la Fuente^1,2,3

¹National Scientific and Technical Research Council (CONICET), Godoy Cruz 2290, C1425 Cdad. Autónoma de Buenos Aires, Argentina.

Neuroscience of consciousness

|December 29, 2025

概括

一种迷幻化合物psilocybin在自然场景感知过程中改变视觉注意力. 高剂量会增加对突出区域的关注,并导致更多的探索性眼动,影响我们处理视觉信息的方式.

科学领域:

神经科学是一个神经科学.
心理药理学心理药理学
认知科学认知科学

背景情况:

像psilocybin这样的迷幻化合物深刻地改变了意识的感知.
这些改变对复杂的视觉引导行为的影响尚未得到充分理解.
研究psilocybin对视觉突出处理的影响对于理解其认知影响至关重要.

研究的目的:

研究psilocybin如何调节在自然场景感知过程中的视觉突出处理.
分析与计算突出度地图相关的凝视模式.
探索这些感知变化的神经相关性.

主要方法:

23名参与者接受了眼睛追踪任务,自行盲目的低剂量和高剂量的psilocybin.
自然主义设计,对参与者和研究人员未知的实验条件.
对基于深度学习的计算突出度图进行分析的凝视模式;静止状态EEG记录.

主要成果:

高剂量的psilocybin增加了对突出图像区域的固定,并减少了相互固定距离.
视觉扫描变得更加探索性和不那么可预测,由香农表示.
EEG显示宽带光谱功率降低和Lempel-Ziv复杂度增加;三角形功率与突出度量有负相关性.

结论:

西显著改变了注意力动态和视觉突出处理.
它会引起对视觉突出点的高度敏感性和更局部,但探索性的凝视行为.
研究结果表明,psilocybin对视觉感知和注意力的影响有神经生物学基础.

关键词:

关注注意力注意力注意力注意力眼睛跟踪眼睛跟踪感知感知感知感知这种药物是psilocybin.突出突出突出突出突出

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