老年患者的快速进展的双边梅毒视觉神经炎:一个病例报告
Masahiko Funatsu1, Makiko Wakuta1, Ayano Sakuma1
1Ophthalmology, Yamaguchi University, Ube, JPN.
Cureus
|December 29, 2025
概括
老年患者的梅毒视神经炎 (SON) 呈现出不良的视觉预后,尽管得到了及时的治疗. 晚年和严重的初始视力丧失是影响这种罕见疾病结果的关键因素.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 神经科学是一个神经科学.
背景情况:
- 梅毒性视觉神经炎 (SON),是Treponema pallidum感染的并发症,通常在接受青素治疗时具有良好的结果.
- 然而,患有严重初始视力障碍或快速进展的老年患者可能面临更差的预后.
研究的目的:
- 突出临床挑战和老年人中SON的不良预后因素.
- 呈现一种罕见的双边视觉功能障碍的罕见病例,尽管进行了最佳的管理,但视觉功能障碍迅速进展.
主要方法:
- 一位80岁的老妇人患有急性双侧视力丧失的详细案例分析.
- 综合眼科检查,实验室检查 (RPR,TPHA) 和治疗反应评估.
- 双边SON与神经网膜炎的文档,包括用静脉注射青素,Triamcinolone亚特胺和口服阿莫西林治疗.
主要成果:
- 尽管早期诊断和高剂量静脉注射青素,视力恢复是最小的,持续严重的视力障碍.
- 炎症征兆有所改善,但血清学标位 (RPR) 仍然低阳性.
- 先进的干预措施并没有显著改善视觉功能.
结论:
- 患有SON的老年患者甚至在适当治疗的情况下也可能有不良的视觉预后.
- 患者的年龄和最初的疾病严重程度是显著的预后因素.
- 眼科医生必须在老年患者中缓和视力恢复的预期,这些老年患者最初的SON呈现严重.
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