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Updated: Jan 7, 2026

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SARS-CoV-2非结构蛋白1通过降低RNA聚合酶II水平来抑制宿主转录

Jianfang Li1,2, Kang Wang1, Jie Wang1,3

  • 1Department of Basic Research, Guangzhou National Laboratory, Guangzhou 510005, China.

iScience
|December 29, 2025
PubMed
概括

SARS-CoV-2非结构蛋白1 (NSP1) 通过降低RNA聚合酶II水平来抑制宿主基因转录. 这项研究揭示了广泛的mRNA下调,为冠状病毒与宿主相互作用和治疗提供了洞察力.

关键词:
分子生物学分子生物学

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