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用天然激动剂TRLW-2准孕妇X受体中的一个独特的结合口袋,可以改善小鼠性结肠炎

Shangrui Rao1, Yi Mei2, Lingyan Shi1

  • 1Department of Colorectal and Anal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Frontiers in pharmacology
|December 29, 2025
PubMed
概括

研究人员确定了一个新的孕妇X受体 (PXR) 结合部位 (口袋1-5) 和一种天然化合物,TRLW-2 (catechin),用于治疗性结肠炎 (UC). 在临床前模型中,TRLW-2显示出抗炎和治疗作用.

关键词:
在TRLW-2中使用.细胞的增殖细胞的增殖.有一个独特的绑定口袋.怀孕前的X受体受体性结肠炎是一种虚拟选 虚拟选 虚拟选

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