减轻绝经后妇女抑郁症状的最佳运动方式和剂量:随机对照试验的系统审查和网络元分析
Peiming Xu1, Rui Guo2, Lei Yang3
1School of Physical Education, Shandong University, Jinan, China.
Frontiers in psychology
|December 29, 2025
概括
抵抗和心身炼在减轻绝经后妇女抑郁症状方面最有效. 一个最佳的运动剂量为750METs-min/week,遵循U形曲线以获得最大的益处.
科学领域:
- 运动科学运动科学
- 老年学是一门学科.
- 精神病学是一个精神病学.
背景情况:
- 抑郁症状是绝经后妇女的一个重大问题.
- 运动是一种公认的非药物治疗方法,但最佳的方法和剂量尚不清楚.
研究的目的:
- 确定最佳的运动方式和剂量,以缓解绝经后妇女的抑郁症状.
- 进行系统性审查和网络元分析 (NMA) 与基于模型的网络元分析 (MBNMA) 进行剂量反应关系.
主要方法:
- 对五个随机对照试验 (RCT) 数据库进行系统搜索.
- 包括33个RCT,共有2607名参与者.
- 使用R软件执行NMA和剂量反应MBNMA,使用RoB 2工具评估偏差风险.
主要成果:
- 所有四种运动类型 (抵抗,心身,有氧,联合) 都显著降低了抑郁症状.
- 抵抗运动 (SMD: -0.90) 和心身运动 (SMD: -0.75) 显示出最大的潜力.
- 观察到一个U形的剂量反应,最佳剂量约为750METs-min/week,超过1,130METs-min/week的效果减弱.
结论:
- 抵抗和心身运动为绝经后妇女的抑郁症提供了最大的治疗潜力.
- 确定了一个~750 METs-min/week的最佳运动剂量,具有U形剂量反应曲线.
- 研究结果支持个性化炼处方,用于管理这一群体中抑郁症状.
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