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Updated: Jan 7, 2026

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三级淋巴体结构通过IFN-γ-JAK-STAT依赖的非典型记忆B细胞分化驱动异位移植排斥

Lijie Ma1,2,3, Shiming Gong1,2,3, Jianchen Fang4

  • 1Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Frontiers in immunology
|December 29, 2025
PubMed
概括

肝脏全移植中的三级淋巴体结构 (TLS) 与排斥和纤维化相关. 这些结构通过非典型的记忆B细胞和IFN-γ形成,导致肝细胞损伤,但可以在治疗上准.

关键词:
不典型的记忆B细胞B细胞活体捐赠者的肝脏移植移植移植后的肝脏纤维化移植后的肝脏排斥三级淋巴体结构的第三级淋巴体结构

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