在成年人中,与状况相关的后结膜异常的模式
Andrea Enerstad Bolle1,2, Silvana Sarria-Estrada3, Thomas Bonduelle4
1Department of Neurology, Odense University Hospital, Odense, Denmark.
Annals of clinical and translational neurology
|December 29, 2025
概括
在状态 (SE) 中的扩散权重成像异常通常涉及皮质或海马. 额外的乳头或小脑干扰表明预后更差,广泛的模式与较差的结果有关.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 神经科学是一个神经科学.
背景情况:
- 周期性扩散权重磁共振成像异常 (DWI-PMAs) 在状态 (SE) 中已知.
- 关于DWI-PMA模式及其在SE的预后意义的数据有限.
研究的目的:
- 系统地审查和元分析DWI-PMA模式在第一次非麻醉性SE.
- 调查不同DWI-PMA模式对患者结果的预后影响.
主要方法:
- 系统审查和个人参与者数据的元分析.
- 包括与成人患者进行的观察性研究,这些患者首次经历非麻醉性SE和DWI-PMA.
- 来自报告≥10名患者的作者邀请的数据共享.
主要成果:
- 分析了161项研究和531名患者,确定了6种DWI-PMA模式.
- 纯海马体DWI-PMA与年轻的年龄,已知的和低死亡率有关.
- thalamic或小脑干扰,双边DWI-PMA和>4个受影响的皮层叶片独立预测了功能不良的结果.
- 在DWI-PMA横向化和性放电横向化之间发现了强烈的一致性.
结论:
- 在SE中DWI-PMA通常起源于皮质和/或海马.
- thalamic和小脑干扰,以及广泛的DWI-PMA,与更糟糕的结果有关.
- 侧面性或泛性周期性排泄与乳头膜干扰相关.
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