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Updated: Jan 7, 2026

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

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Nerofe+ldDox从核ST2释放c-Jun,以重新编程mtKRAS瘤中的免疫微环境

Joel Ohana1, Uziel Sandler1,2, Benjamin A Weinberg3

  • 1Immune System Key (ISK) Ltd., Jerusalem 9746009, Israel.

Oncotarget
|December 29, 2025
PubMed
概括

尼罗菲加低剂量多克索鲁比辛 (ldDox) 联合治疗有效地重塑突变KRAS (mtKRAS) 癌症中的瘤微环境. 这种治疗促进了免疫细胞的透,并减少了KRAS的表达,提供了一个有前途的新疗法策略.

关键词:
这是Nerofe的.这是一个ST2受体.突变的克拉斯KRAS.核免疫调节是一种核免疫调节.瘤免疫的微环境

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