饮食中的教理粉可以增强牛肉对脂多糖刺激的肠道弹性
Jiakun Yan1, Qimeng Shi1, Luqi Wang1
1Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, Hubei, 430023, China.
Journal of animal science
|December 29, 2025
概括
卡特丘粉 (CP) 有效地对抗受脂多糖化物 (LPS) 挑战的肉的炎症和氧化应激. 这种植物性添加剂支持肠道屏障功能,在家禽养殖中显示出作为安全抗生素替代品的希望.
科学领域:
- 动物科学动物科学
- 营养科学 营养科学
- 兽医医学 兽医医学 兽医医学
背景情况:
- 禽业正在寻找替代抗生素的方法来维持肠道健康.
- 植物添加剂对于预防炎症和改善肠道完整性至关重要.
- 富含多的Catechu粉 (CP) 正在被研究其潜在的益处.
研究的目的:
- 为了研究教理粉 (CP) 作为肉抗生素替代品的疗效.
- 评估CP对肠道炎症,屏障功能和抗氧化能力的影响.
- 评估CP补充剂和脂多糖 (LPS) 之间的相互作用.
主要方法:
- 一百只肉被分为对照组和补充CP的组 (1,000 mg/kg).
- 在第29天,鸟类被挑战用脂多糖 (LPS) 或盐水.
- 分析了炎症标志物,氧化应激指标,状组织形态学和屏障功能基因.
主要成果:
- 补充CP显著减轻LPS诱导的炎症,减少关键的炎症基因表达 (IFN-γ,TNF-α,IL-8).
- 通过降低过氧化 (H2O2) 和甲 (MDA) 水平,CP减轻了LPS诱导的氧化应激.
- CP恢复了肠道屏障的完整性,增加了状的高度和Claudin1和Mucin2基因表达.
结论:
- 饮食CP有效缓解LPS诱导的免疫应激和肉肠道损伤.
- CP抑制炎症反应和氧化损伤,支持其作为功能性料添加剂的作用.
- 在家禽生产中,Catechu粉显示出作为可行的抗生素替代品的潜力.
相关概念视频
Dietary Connections
In biological systems, most metabolic pathways are interconnected. The cellular respiration processes that convert glucose to ATP—such as glycolysis, pyruvate oxidation, and the citric acid cycle—tie into those that break down other organic compounds. As a result, various foods—from apples to cheese to guacamole—end up as ATP. In addition to carbohydrates, food also contains proteins and lipids—such as cholesterol and fats. All of these organic compounds are used as energy sources to produce...
Protein Digestion
Protein digestion begins in the stomach, where the highly acidic environment can easily disrupt protein structure by exposing the peptide bonds of polypeptide chains. After polypeptide chains are broken into individual amino acids by a series of digestive enzymes, the amino acids are transported to the liver via the bloodstream to produce energy.
Carbohydrate Digestion
Carbohydrate digestion and metabolism break down simple and complex carbohydrates from food into saccharides (i.e., sugars) for the body to use as energy. Carbohydrate digestion starts in the mouth during mastication, or chewing. The masticated carbohydrates remain intact in the stomach. Digestion resumes in the duodenum of the small intestine, where pancreatic alpha-amylase and brush border enzymes of the microvilli convert complex carbohydrates to monosaccharides. Finally, the monosaccharides...
Drugs Affecting GI Tract Motility: Bulk-Forming and Stimulant Laxatives
Laxatives enhance bowel movements and alleviate constipation. They augment the stool's bulk, stimulate intestinal muscle contractions, draw water into the intestines, or soften the stool. There are five key types of laxatives: bulk laxatives, stimulant laxatives, osmotic laxatives, stool softeners, and lubricant laxatives.
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This makes...
Bulk-forming laxatives, such as psyllium, methylcellulose, and polycarbophil, absorb water in the intestine, increasing stool bulk and promoting bowel movement. This makes...
Regulation of Food Intake
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...


