长期使用的乙格斯特勒植入物与其他避孕药的五年成本后果分析
Vanessa Perez Patel1, Kevin Collins1, Klaas Heinemann2
1Organon, Jersey City, NJ, USA.
Journal of medical economics
|December 29, 2025
概括
乙格斯特勒植入物是五年内最具成本效益的长效可逆避孕 (LARC),可以预防大多数怀孕并降低医疗保健成本. 支持其使用可以改善患者的治疗结果和成本效益.
科学领域:
- 生殖健康 生殖健康
- 卫生经济学 卫生经济学
- 药物经济学 药物经济学
背景情况:
- 长效可逆避孕 (LARC) 提供了延长的怀孕预防,减少了用户负担.
- 乙格斯特勒植入物在LARC方法中提供了最高的疗效,但起始成本较高.
- 这项研究评估了乙凝植入物的首付费用是否可以通过预防怀孕和减少相关支出来抵消.
研究的目的:
- 评估与其他激素避孕药相比,乙格斯特勒植入物的成本效益.
- 为了确定预防怀孕和降低医疗保健费用是否抵消了乙格斯特勒植入物的收购费用.
- 分析停止使用避孕方法对整体成本的影响.
主要方法:
- 一个离散的马尔科夫链模型模拟了1000名年龄在18-49岁的妇女在5年内怀孕的结果.
- 他们比较了8种荷尔蒙避孕方法,包括口服避孕,注射,阴道环,贴片,宫内节育器和乙格斯特勒植入物.
- 该模型从美国管理护理的角度考虑了避孕成本,典型使用失败率,停药率,怀孕成本和医疗保健资源利用率.
主要成果:
- 在5年内,以格斯特勒植入物导致最少的怀孕 (60) 和最低的女性成本 (3428美元).
- 宫内器械 (IUD) 是下一个最有效和最具成本效益的选择.
- 口服避孕药和其他方法的怀孕率和成本显着更高,而停用率是主要的成本驱动因素.
结论:
- 乙格斯特勒植入物是5年期间最具成本效益的避孕选择,最大限度地减少怀孕和相关的医疗保健费用.
- 促进启动和延续etonogestrel植入物的政策可以改善临床结果和经济效率.
- 戒断避孕药对整体的成本效益有很大影响,这凸显了方法坚持的重要性.
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