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Updated: Jan 7, 2026

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PARP 和 PARP 抑制剂:分子机制和临床应用

Fei Wang1, Zhuyi Guo2, Michael J Carr3,4

  • 1Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Molecular biomedicine
|December 29, 2025
PubMed
概括

多 (ADP-ribose) 聚合酶 (PARP) 是DNA修复和细胞信号传递中的关键酶. PARP 抑制剂 (PARPi) 在癌症和其他疾病中表现有前途,但耐药性和副作用需要新的治疗策略.

关键词:
癌症 癌症 癌症 癌症临床应用 临床应用在巴黎的巴黎.在PARPs中,PARPs是非常重要的.病毒 病毒 病毒

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