在NHANES 2011-2014年糖尿病老年人中,身体活动和认知功能的值效应
Jigang Ren1,2, Huibiao Li1, Li Liufu1
1College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Aging clinical and experimental research
|December 29, 2025
概括
身体活动对患有糖尿病的老年人有益于认知功能. 最佳效益在490MET分钟/周左右观察到,在更高的运动量下没有进一步的改善.
科学领域:
- 老年学是一门学科.
- 运动生理学 运动生理学
- 神经科学是一个神经科学.
背景情况:
- 老龄化过程中的认知能力下降是一个公共卫生问题,特别是在糖尿病患者 (DM) 中.
- 虽然已知运动可以改善认知功能,但老年人患有DM的具体剂量反应关系尚不清楚.
研究的目的:
- 调查身体活动对患有DM的老年人认知功能的值效应.
- 确定在这个人群中保持认知功能的最佳体力活动量.
主要方法:
- 来自2011-2014年国家健康和营养检查调查 (NHANES) 的925名老年参与者的分析.
- 使用动物流利性测试 (AFT) 和数字符号替换测试 (DSST) 评估认知功能.
- 使用权重线性回归和受限立方线分析,包括两部分线性回归模型,以检查关系并确定值效应.
主要成果:
- 在对混因素进行调整后,发现身体活动水平和认知功能得分 (AFT和DSST) 之间存在正相关性.
- 值分析显示,FT分数低于490MET-min/week和DSST分数低于1,120MET-min/week的显著积极关系.
- 观察到一种和效应,表明认知效益在超出这些身体活动值之后停滞不前.
结论:
- 在患有DM的老年人中,身体活动和认知功能之间存在一个反转的U形关系.
- 大约490MET分钟/周的体育活动似乎是最佳的认知功能在这个人口.
- 建议使用像计步器和加速度计这样的客观测量方法进行进一步的研究,以验证这些发现.
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