在听觉选择性空间注意力过程中,与年龄相关的听力损失中的动态大脑功能连接
Hongxing Liu1,2, Yanru Bai1,2,3,4, Mingkun Guo1,2
1Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China.
GeroScience
|December 29, 2025
概括
与年龄相关的听力损失 (ARHL) 损害了听觉感知. 大脑网络分析显示,ARHL改变了功能连接,右侧顶叶对注意力至关重要.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 认知神经科学 认知神经科学
背景情况:
- 与年龄相关的听力损失 (ARHL) 是一种普遍影响老年人听觉感知的疾病.
- 在听觉空间选择性注意力期间,ARHL中大脑功能连接的动态模式仍未得到充分探索.
- 了解这些神经动态对于开发有针对性的干预措施至关重要.
研究的目的:
- 在听觉空间选择性注意力过程中调查与年龄相关的听力损失 (ARHL) 中的动态大脑功能连接.
- 识别与听力损失严重程度相关的大脑网络拓学的变化.
- 探索ARHL听觉注意力缺陷背后的神经机制.
主要方法:
- 招募了32名不同程度听力损失的老年人.
- 设计了一个听觉空间选择性注意任务,并记录了脑电图 (EEG) 信号.
- 构建多层时间变化的脑网络,使用多个时间窗口来分析动态功能连接和网络拓.
主要成果:
- 行为分析显示,听力损失严重程度与听觉空间选择性注意力表现之间存在负相关性.
- 多层网络分析表明,层间连接性增加,模块化性降低,参与系数提高,听力损失恶化.
- 核心层分析确定了右额叶的关键作用,并建议右前额叶和前额叶的补偿连接.
结论:
- 与年龄相关的听力损失恶化改变了动态的大脑功能连接,其特点是模块化减少和跨模块相互作用增加.
- 在ARHL的背景下,右头顶叶对听觉空间选择性注意力至关重要.
- 这些发现为精确的听觉康复策略提供了潜在的神经科学见解和生物标志物.
更多相关视频
09:01A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance
Published on: May 7, 2014
10.5K
07:14A Method to Study Adaptation to Left-Right Reversed Audition
Published on: October 29, 2018
6.8K
相关概念视频
Hearing
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
Higher Mental Functions of the Brain: Language
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Auditory Pathway
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
Neuroplasticity
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
Auditory Perception
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the cochlea, a...
Perceiving Loudness, Pitch, and Location
The human brain perceives pitch through two primary mechanisms reflected in place theory and frequency theory. Each mechanism describes how sound waves are interpreted as specific pitches by the brain, offering insights into the intricate processes of auditory perception.
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
Place theory, or place coding, suggests that different pitches are heard because various sound waves activate specific locations along the cochlea's basilar membrane. The brain determines the pitch of a sound by identifying...
