评估光学连贯性断层扫描-血管学发现,在形患者治疗加速交叉链接协议的评估
Erhan Kanat1, Alper Mete, Sevim Ayça Seyyar
1Elbistan State Hospital (E.K.), Ophthalmology Clinic, Kahramanmaraş, Turkey; and Ophthalmology Department (A.M., S.A.S.), Gaziantep University Hospital, Gaziantep, Turkey.
Eye & contact lens
|December 29, 2025
概括
角膜的加速交叉链接 (A-CXL) 暂时减少了视网膜微血管化,表面的变化大多是逆转的. 深层视网膜循环变化持续存在,这表明对视网膜外侧的长时间影响.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜成像 视网膜成像
- 角质交叉连接的交叉连接
背景情况:
- 角膜是一种渐进的角膜疾病.
- 加快角膜交叉链接 (A-CXL) 是一种治疗角膜的方法.
- A-CXL对视网膜微血管结构的影响尚未完全理解.
研究的目的:
- 为了研究A-CXL对视网膜微血管化的影响,在角质患者.
- 用光学相干断层扫描-血管学 (OCT-A) 来评估视网膜和视觉神经头部参数的变化.
主要方法:
- 用A-CXL治疗的角质患者的49只眼睛被分析.
- 使用OCT-A测量视网膜和视神经头部参数.
- 测量是在手术前,手术后1周,1个月,6个月进行的.
主要成果:
- 表面毛细管血管密度 (SCP-VD) 在治疗后的早期减少,在叶和叶区域,部分恢复6个月.
- 深毛细管血管密度 (DCP-VD) 在多个区域显著减少,一些变化在6个月内持续存在.
- 中部黄斑厚度 (CMT) 降低,6个月后,DCP-VD,视网膜深毛细管血流,CMT和胆毛细管血流持续减少.
结论:
- 角质的A-CXL治疗诱导了表面和深视网膜血管的显著早期变化.
- 虽然表面变化似乎大多是可逆的,但深层视网膜微循环的持续变化表明对外视网膜的长期,潜在的亚临床影响.
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