复发性鼻癌:治疗结果和发病率
Vittorio Rampinelli1,2, Claudia Lodovica Modesti1,2, Alessandro Vinciguerra3
1Unit of Otorhinolaryngology - Head and Neck Surgery, ASST Spedali Civili.
Current opinion in otolaryngology & head and neck surgery
|December 29, 2025
概括
回复性鼻癌 (NPC) 的最佳管理平衡了疗效和毒性. 内镜手术为切除的病例提供了更好的结果,而对不可切除的瘤来说,再辐射是关键.
科学领域:
- 在瘤学瘤学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 辐射瘤学 辐射瘤学
背景情况:
- 复发性鼻癌 (NPC) 提出了复杂的管理挑战.
- 为了获得最佳的结果,平衡治疗疗效与患者毒性至关重要.
研究的目的:
- 审查经常性NPC的当前管理策略.
- 评估不同治疗方式的疗效和毒性概况.
主要方法:
- 关于NPC重复管理的最新证据的文献综述.
- 对瘤控制,功能结果和毒性数据的分析.
主要成果:
- 与再辐射相比,内镜鼻切除术为可切除的复发性NPC提供了更高的生存率和更低的发病率.
- 对无法切除的瘤来说,再照射 (re-RT) 是至关重要的,需要仔细的患者选择和毒性管理.
- 影像学和爱斯坦-巴尔病毒DNA监测方面的进步有助于早期检测和风险分层.
结论:
- 个性化,多学科的决策对于管理经常性NPC是必不可少的.
- 切除可切除的疾病最好采用外科切除;对于不可切除的疾病,重复切除是标准.
- 系统疗法和免疫疗法在复发性,非转移性NPC中发挥的作用有限.
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