内静脉微波切除与下肢静脉的射频切除:系统性审查和元分析
Dawood Javed1, Arsalan Nadeem2, Abdullah Javed2
1Lahore Medical and Dental College, Lahore, Pakistan.
Journal of vascular and interventional radiology : JVIR
|December 29, 2025
概括
微波切除 (MWA) 和射频切除 (RFA) 在治疗下肢静脉治疗中同样有效,在一年后显示出类似的高闭塞率和生活质量改善.
科学领域:
- 血管外科 血管外科
- 最少侵入性手术的方法
- 医疗器械技术 医疗器械技术
背景情况:
- 下肢静脉 (LLVV) 影响着相当一部分人群,影响生活质量.
- 静脉内热切除法技术,包括微波切除 (MWA) 和射频切除 (RFA),已成为LLVV的治疗方法.
研究的目的:
- 进行一项元分析,比较内静脉微波切除 (MWA) 与射频切除 (RFA) 的疗效和安全性,用于治疗下肢静脉 (LLVV).
主要方法:
- 在主要数据库 (PubMed,Embase,Scopus,Web of Science) 进行了系统的文献搜索,寻找相关的随机临床试验和观察性研究.
- 主要终点包括闭塞率和生活质量 (QoL),次要结果评估住院治疗,手术时间,失血和不良事件.
- 使用Review Manager 5.4进行了随机效应元分析,包括敏感性分析来评估发现的稳定性.
主要成果:
- 四项涉及887名患者 (436名MWA,451名RFA) 的研究被纳入了分析.
- 无论是MWA还是RFA,都显示出高的一年封闭率 (MWA: 97.5%;RFA: 98.0%),两种技术之间没有统计学上显著的差异.
- 生活质量得分和不良事件发生率在MWA和RFA之间是可比的,尽管灵敏度分析表明RFA可能与住院日数减少和手术时间缩短有关.
结论:
- 静脉内微波切除术 (MWA) 和射频切除术 (RFA) 是下肢静脉瘤的安全和高度有效的治疗选择.
- 这两种技术都实现了优异的长期阻塞率和可比的生活质量的改善.
- 在MWA和RFA之间做出选择时,可以考虑诸如手术时间和住院等因素,其中RFA在灵敏度分析中显示出轻微的优势.
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