相关实验视频

Updated: Jan 7, 2026

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure
08:25

Advanced 3D Liver Models for In vitro Genotoxicity Testing Following Long-Term Nanomaterial Exposure

Published on: June 5, 2020

7.2K

扩展决策树:预测慢性毒性潜力和安全摄入水平

Szabina Stice1, Timothy Adams2

  • 1US Food and Drug Administration, Human Foods Program, Office of Food Chemical Safety, Dietary Supplements, and Innovation. 5001 Campus Drive, College Park, MD 20740, USA.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
|December 29, 2025
PubMed
概括

美国食品和药物管理局开发了扩展决策树 (EDT),以改善化学毒性评估. 这个更新的结构-活动关系工具增强了监管毒理学和毒理学关注查的门.

关键词:
克拉默的分类方案 克拉默的分类方案克莱默等人. 克莱默等人. (1978) 决策树 (CDT) 是指一个决定树.扩展的决策树 (EDT)毒理学关注的门 (TTC)长期有毒潜在的慢性毒性相对有毒的潜在毒性相对.安全评价安全评估查和优先考虑工作.

更多相关视频

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox05:47

In Silico Modeling Method for Computational Aquatic Toxicology of Endocrine Disruptors: A Software-Based Approach Using QSAR Toolbox

Published on: August 28, 2019

14.5K
Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation16:02

Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation

Published on: February 10, 2023

3.2K

相关概念视频

Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
1.7K
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
3.1K