根据年龄和性别,食物过敏原敏感化的三个不同模式
1Department of Otorhinolaryngology, Yonsei University Wonju College of Medicine, Wonju, Korea.
Scientific reports
|December 29, 2025
概括
这项研究揭示了韩国不同年龄组和性别的不同食物过敏原敏感化模式. 植物性和贝类过敏在青春期和晚年成年期达到顶峰,而动物性过敏在幼儿中最高.
科学领域:
- 免疫学 免疫学 免疫学
- 过敏学 过敏学
- 流行病学 流行病学
背景情况:
- 有限的大规模人口数据存在于韩国的食物过敏原敏感化模式.
- 了解年龄和性别特定的敏感性对于公共卫生至关重要.
- 多种过敏原同时测试 (MAST) 提供了一个全面的数据集用于分析.
研究的目的:
- 分析特定年龄和性别对各种食物过敏原的敏感化模式.
- 调查植物性,动物性和贝类过敏原类别之间的敏感性差异.
- 为韩国提供以人口为基础的关于食物过敏趋势的数据.
主要方法:
- 分析了全国344,678名疑似过敏患者的MAST结果.
- 包括56种食物过敏原的特定免疫球蛋白E (IgE) 水平.
- 敏感性定义为第2类 (0.70-3.49 IU/mL) 或更高的IgE水平.
主要成果:
- 植物性食物过敏原敏感性在1-20岁和51-70岁的年龄达到顶峰.
- 动物性食物过敏原敏感性在1-10岁的年龄段很高,然后下降.
- 贝类过敏原敏感性在11-20岁时达到峰值,并保持一致直到61-70岁.
- 与女性相比,男性对植物性和贝类过敏原的敏感度更高.
- 对于动物性食物过敏原,没有观察到显著的性别差异.
结论:
- 食物过敏原敏感性因年龄和过敏原类别而异.
- 对于植物性,动物性和贝类过敏原,存在不同的与年龄相关的敏感化轨迹.
- 性别影响特定食物过敏原组的敏感化模式,特别是植物性和贝类.
相关概念视频
Allergic Reactions
31.9K
Overview
31.9K
Hypersensitivities
6.9K
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
6.9K
Cross-reactivity
32.8K
Overview
32.8K
Allergic Drug Reactions
1.3K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.3K
Development of Immunocompetence
769
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
769
Two-Way ANOVA
3.3K
The two-way ANOVA is an extension of the one-way ANOVA. It is a statistical test performed on three or more samples categorized by two factors - a row factor and a column factor. Ronald Fischer mentioned it in 1925 in his book 'Statistical Methods for Researchers.'
The two-way ANOVA analysis initially begins by stating the null hypothesis that there is an interaction effect between the two factors of a dataset. This effect can be visualized using line segments formed by joining the...
The two-way ANOVA analysis initially begins by stating the null hypothesis that there is an interaction effect between the two factors of a dataset. This effect can be visualized using line segments formed by joining the...
3.3K


