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冠状动脉CTA的不同重建算法的差异,表明冠状动脉周周脂肪组织衰减

Yuxuan Zhu¹, Jiajie Zhu¹, Xin Ding¹

¹Department of Radiology, Nanjing BenQ Medical Center, The Affiliated BenQ Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.

Scientific reports

|December 29, 2025

概括

冠状动脉炎症的脂肪减弱指数 (FAI) 根据冠状动脉计算机断层扫描血管学 (CCTA) 重建算法有显著的变化. 在多中心研究中,标准化协议对于准确,可重复的FAI结果至关重要.

科学领域:

心血管成像 - 心血管成像
医学物理医学物理
放射学放射学是一门学科.

背景情况:

脂肪减弱指数 (FAI) 是冠状动脉炎症的敏感生物标志物,可通过冠状动脉计算机断层扫描血管学 (CCTA) 测量.
在CCTA中使用的不同图像重建算法可能会影响FAI测量.

研究的目的:

在CCTA上使用三个重建算法评估FAI测量的差异:深度学习图像重建 (DLIR-H),自适应统计代重建-Veo (ASiR-V50%),和过后投影 (FBP).

主要方法:

根据冠状动脉斑块的存在 (正常,没有斑块,非化,混合,化) 患者被分类.
每个算法 (DLIR-H,ASiR-V50%,FBP) 在冠状动脉中测量了FAI,心周脂肪组织衰减和图像噪声.
进行了统计分析,以比较算法和斑块组之间的测量结果.

主要成果:

周心脂肪组织衰减在算法之间没有显著差异.
用DLIR-H的FAI值最高,用ASiR-V50%的中间值最高,用FBP的最低,所有差异都是统计学上显著的.
与FBP相比,DLIR-H表现出优越的图像降噪.

结论:

重建算法的选择显著影响CCTA中的FAI测量.
标准化重建协议对于多中心和纵向研究至关重要,以确保可重复和可比的FAI结果.

关键词:

算法算法是一种算法.在冠状动脉中,CTA 脂肪减弱指数是指脂肪减弱指数.心灵心脏心脏的心脏心脏心脏

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