GDM修改了妊娠期体重增加与妊娠结果的关联:基于人口的队列研究
Wen Jin1, Ye Huang1,2, Yiwen Qiu2
1Department of Medical Records, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Journal of translational medicine
|December 30, 2025
概括
孕期糖尿病 (GDM) 影响孕期体重增加 (GWG) 如何影响怀孕结果. 个性化体重管理对于患有GDM的妇女来说至关重要,以减轻妊娠年龄婴儿的风险.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 内分泌学 在内分泌学.
背景情况:
- 妊娠期糖尿病查时间可能会影响妊娠期体重增加 (GWG).
- 与GDM状态相关的GWG对妊娠结果的影响需要进一步澄清.
- 了解这些关联对于优化母婴健康至关重要.
研究的目的:
- 调查GDM对GWG在不同怀孕期和各种怀孕结果之间的关联的影响.
- 为了确定GDM状态是否会改变GWG和不良妊娠结果之间的关系.
主要方法:
- 总共分析了GWG,并在口服葡萄糖耐受性测试 (OGTT) 之前和之后进行分类.
- 计算了GWG率,并将其分类为不充分,正常或过度.
- 使用后勤回归和交叉分析来评估GWG协会和GDM效果的修改.
主要成果:
- 无论是GDM还是非GDM群体,都显示出对妊娠年龄大 (LGA),巨和剖腹产的风险增加,GWG率更高.
- 在患有GDM的女性中,GWG和LGA风险之间的关联显著更强.
- 不充分的GWG在非GDM女性中增加了SGA和LBW风险,GDM女性没有看到这种效果.
结论:
- 在GWG和怀孕结果之间的关系,特别是在OGTT之后,受到GDM状态的显著影响.
- 这些发现凸显了对有GDM的孕妇进行个性化体重管理策略的必要性.
- 量身定制的GWG建议可以帮助改善怀孕结果并减少并发症.
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