结核病治疗抑郁症的认知疗法:巴基斯坦多中心混合型1型有效性实施试验的过程评估协议
Fayaz Ahmad1, Maryiam Rahim1, Fatima Khalid Qazi2
1Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan.
Trials
|December 30, 2025
概括
这项研究评估了对巴基斯坦结核病患者抑郁症的认知行为疗法 (CBT) 干预. 过程评估评估了实施结果,以指导未来的综合心理健康护理扩展.
科学领域:
- 实施科学 实施科学
- 公共卫生 公共卫生
- 心理健康服务研究 心理健康服务研究
背景情况:
- 结核病 (TB) 和抑郁症经常同时发生,特别是在低收入和中等收入国家 (LMICs),影响治疗坚持.
- 巴基斯坦面临着一个重大的公共卫生挑战,结核病的高发病率和同时出现的抑郁症.
- 结核病抑郁症认知疗法 (CONTROL) 试验旨在通过将认知行为疗法 (CBT) 整合到结核病护理中来解决这一问题.
研究的目的:
- 使用Proctor的框架进行CONTROL试验的过程评估.
- 评估关键的实施结果:可接受性,采用性,可行性,适当性,忠实性,透性和可持续性.
- 在巴基斯坦的常规结核病护理计划中,为在巴基斯坦的常规结核病护理计划中进行综合CBT干预的潜在扩展提供信息.
主要方法:
- 在巴基斯坦Khyber Pakhtunkhwa的CONTROL随机对照试验中嵌入了一种混合方法的过程评估.
- 使用验证的实施结果措施 (IAM,AIM,FIM,AMHR,CTS-R等) 进行定量数据收集. 和行政日志.
- 通过半结构面试和焦点小组讨论进行定性数据收集,以主题分析和三角分析数据.
主要成果:
- 在12个结核病护理机构的随机化后8,24和32周的数据收集点.
- 描述性地分析的定量数据.
- 定性数据以主题分析,然后对发现进行三角分析,以提供全面的见解.
结论:
- 过程评估将为结核病护理机构中CBT干预措施的实施提供关键的见解.
- 确定了将心理健康护理整合到结核病控制计划中的障碍和促进因素,以实现未来的可扩展性.
- 调查结果将指导决策者将心理健康干预措施纳入常规结核病护理的可行性,从而有可能改善患者的治疗结果,并为全球实施科学做出贡献.
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