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Updated: Jul 3, 2026

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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纵向CD4+T细胞样本的单细胞RNA-seq分析揭示了1型糖尿病早期的细胞类型特异性变化

Rahul Biradar1,2, Ubaid Ullah Kalim3,4, Tapio Lönnberg1,2

  • 1Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.

Genome medicine
|December 30, 2025
PubMed
概括

单细胞分析揭示了在患有1型糖尿病的儿童中早期的CD4+T细胞转录性变化. 这些发现突出了参与早期免疫失调的关键途径和基因调节者,用于潜在的诊断和干预.

关键词:
CD4+ T 细胞是 CD4+ T 细胞.规则 规则 规则血清转换是一种血清转换.单细胞RNA测序scrRNA-seqq进行测序.1型糖尿病 (T1D) 是一种糖尿病.

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