在CODING研究中,饮食摄入量与内脏脂肪之间存在显著的反向关联
Shanshan Yu1, Hongwei Zhang2, Jianling Du3
1Department of Endocrinology, First Affiliated Hospital of Dalian Medical University, Dalian, 116011, Liaoning, China.
Scientific reports
|December 30, 2025
概括
调整为体重的较高摄入量与明显较低的内脏脂肪有关. 这一发现表明,体重调整的摄入量可能是通过减少内脏肥胖来预防心血管疾病的关键营养策略.
科学领域:
- 营养科学 营养科学
- 心血管疾病研究研究
- 肥胖研究 肥胖研究
背景情况:
- 过多的内脏脂肪组织 (VAT) 是心血管疾病 (CVD) 的强有力的预测因素,独立于BMI.
- 减少内脏肥胖对于预防心血管疾病至关重要.
- 饮食中的 (Se) 在调节增值税中的作用尚不清楚,之前的研究缺乏直接联系.
研究的目的:
- 研究饮食摄入量与内脏脂肪组织 (VAT) 水平之间的关系.
- 为了强调表达摄入量相对于体重 (μg/kg/d) 对于准确评估的重要性.
主要方法:
- 一项对新foundland人口复杂疾病:环境和遗传学 (CODING) 研究的3244名参与者的横截面研究.
- 通过Willett食物频率问卷 (FFQ) 评估的饮食摄入量.
- 使用双能X射线吸收计 (DXA) 精确测量内脏脂肪组织 (VAT) 质量和体积.
主要成果:
- 在两种性别中,越来越多的饮食摄入量的四分位数 (μg/kg/d) 中,内脏脂肪率显著下降.
- 摄入Se的最高四分位数 (μg/kg/d) 的参与者表现出明显较低的内脏脂肪率 (女性为50.97%,男性为63.75%).
- 体重调整后的Se摄入量 (μg/kg/d) 增加10%与内脏脂肪率下降2.73%,男性和年轻人的效果更强.
结论:
- 这项研究表明,饮食中的Se摄入量 (μg/kg/d) 和VAT之间存在显著的反向关联,解决了之前的不一致性.
- 研究结果强调,只有当Se摄入量与体重相对表达时,这种关系才会明显.
- 适当的体重调整的Se摄入量可能是减少内脏肥胖和改善心血管疾病预防的有价值的营养策略.
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