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Updated: May 6, 2026

A Whole Body Dosimetry Protocol for Peptide-Receptor Radionuclide Therapy PRRT: 2D Planar Image and Hybrid 2D+3D SPECT/CT Image Methods
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放射性药物剂量测量的数字双胞胎:在临床前mCRPC模型中对[177Lu]Lu-rhPSMA-10.1的PBPK建模

Gustavo Costa1,2, Elham Yousefzadeh-Nowshahr1,2, Valentina Vasic1,2

  • 1Department of Nuclear Medicine, Ulm University, 89081 Ulm, Germany.

Cancers
|December 30, 2025
PubMed
概括

基于生理学的药理动力学 (PBPK) 数字双胞胎准确估计[177Lu]Lu-rhPSMA-10.1向放射性核酸治疗的吸收剂量,即使有噪音数据. 这种个性化剂量测量方法确保了前列腺癌患者的可靠治疗优化.

关键词:
在PBPK建模中使用PBPK模型.[177Lu]Lu-rhPSMA-10.1 的时间.数字双胞胎数字双胞胎是什么意思剂量测量方法 剂量测量方法有针对性的放射性核酸治疗.

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