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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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CDK4/6抑制剂对瘤免疫的双重作用

Yiran Si1, Hongli Li1, Yehui Shi2

  • 1Department of Phase I Clinical Trial, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Key Laboratory of Cancer Immunology and Biotherapy, Tianjin 300060, China.

Cancers
|December 30, 2025
PubMed
概括

循环素依赖性激酶4/6 (CDK4/6) 抑制剂通过复杂的机制影响瘤免疫力,影响细胞循环和免疫反应. 需要进一步的研究来优化它们与免疫治疗的结合,考虑到严重的不良事件.

关键词:
这是一种CDK4/6抑制剂.双重影响的双重效应.免疫微观环境 免疫微环境免疫疗法 免疫疗法瘤免疫力 免疫力

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