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Updated: Jun 24, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

在右半球质瘤患者中评估网络完整性,使用基于功能的谱图和特定领域的认知测试

Maximilian Schwendner¹, Leonie Kram¹, Johanna Lackner¹

¹Department of Neurosurgery, Heidelberg University Hospital, Ruprecht-Karls-University Heidelberg, 69120 Heidelberg, Germany.

|December 30, 2025

概括

右半球质瘤经常导致手术前的认知缺陷. 在切除过程中保留特定的大脑区域有助于认知恢复,正如基于功能的曲谱学所示.

科学领域:

神经科学是一个神经科学.
神经外科神经外科
认知科学认知科学

背景情况:

质瘤可以破坏大脑网络和神经功能.
右半球质瘤对更高认知功能的影响比左半球质瘤了解得更少.
评估认知变化及其结构相关性对于患者的治疗结果至关重要.

研究的目的:

评估右半球质瘤患者手术前和手术后的神经认知表现.
使用基于功能的曲谱学,将认知结果与结构性大脑发现相关联.
了解右侧质瘤对认知功能的影响.

主要方法:

对质瘤患者进行前性观察性研究.
在手术前,手术后和3个月的随访期间使用神经认知测试电池.
利用导航式横磁刺激 (nTMS) 进行皮质映射和扩散张力成像 (DTI) 进行基于功能的纤维跟踪.

主要成果:

在手术前,88.8%的患者有认知障碍,特别是精细运动技能,执行功能和处理速度.
随访时认知表现有所改善.
上部纵向 I-III 和下部额头带的参与与特定的认知缺陷相关,包括注意力,执行功能,视觉空间处理和记忆.

结论:

手术前的神经认知缺陷在右半球质瘤中很常见.
节省关键白质道的最大安全切除与认知恢复有关.
基于功能的通道图强调了特定纤维通道参与和认知障碍之间的关联.

关键词:

大脑绘制地图雄辩的质细胞瘤功能引导性手术是指导性手术.神经认知测试是一种神经认知测试.

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