通过流体结构相互作用分析发现上表面声损伤的影响
Manoela Neves1, Anitha Niyingenera1, Norah Delaney1
1Department of Biomedical Engineering, School of Science and Engineering, Duquesne University, Pittsburgh, PA 15219, USA.
Bioengineering (Basel, Switzerland)
|December 30, 2025
概括
声病变会增加空气流阻力,破坏振动对称性,导致声音振荡较弱. 这种生物机械模拟阐明了病变如何导致语音障碍,如失声症.
科学领域:
- 生物力学 生物力学
- 声音科学 声音科学
- 计算建模 计算建模
背景情况:
- 声 (VF) 损伤可能会导致失声症,但它们对发音的精确生物力学影响尚未完全理解.
- 之前的研究还没有将具有病变的现实VF模型集成到计算模拟中,以研究发音.
- 在了解病变形态如何影响VF组织特性和空气流动力学方面存在差距.
研究的目的:
- 研究声病变对喉气流和组织振荡的生物力学影响.
- 通过计算模拟具有病变的现实VF模型,以了解其对语音障碍的贡献.
- 探索由病变引起的形态变化对VF弹性和质性质的影响.
主要方法:
- 从CT扫描数据开发了一个三维,特定于主体的多层VF模型.
- 采用流体结构相互作用 (FSI) 方法来合球气流和VF组织动态.
- 两种FSI模型进行了比较:一种具有嵌入性病变 (出血性息肉),一种没有.
主要成果:
- 损伤略微增加了喉中的空气流阻力.
- 振动对称性被破坏,受影响的VF的振动频率下降.
- 病变导致较弱,较少的节奏振荡,并增加受影响的VF的组织压力.
结论:
- 病变显著改变了发音的生物力学特征.
- 模拟结果与由VF病变引起的语音障碍的临床观察结果一致.
- 这些发现阐明了VF病变导致发声障碍的机制.
相关概念视频
Larynx
4.0K
The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
4.0K
Surface Tension of Fluid
1.3K
Surface tension is a fundamental property of fluids, occurring at the boundary between a liquid and a gas or between two immiscible liquids. This phenomenon arises from the cohesive forces between molecules at the fluid's surface, creating an effect similar to a stretched elastic membrane. Inside each fluid, molecules are equally attracted in all directions by neighboring molecules, but surface molecules experience a net inward force, resulting in surface tension.
Surface tension varies...
Surface tension varies...
1.3K
Standing Waves in a Cavity
1.4K
A household microwave and lasers are examples of standing electromagnetic waves in a cavity. When two conducting metal plates are placed parallel at the nodal planes, it creates a cavity where standing waves are formed. The cavity between the two planes is analogous to a stretched string held at the points x = 0 and x = L. Here, the distance 'L' between the two planes must be an integer multiple of half of the wavelength. The wavelengths that satisfy this condition are given by:
1.4K
Fluid Pressure over Curved Plate of Constant Width
1.9K
When a curved plate of constant width is submerged in a liquid, the pressure acting normal to the plate varies continuously both in magnitude and direction. Calculating the magnitude and location of the resultant force at a point is often challenging for such cases. One of the methods to determine the resultant force and its location involves separately calculating the horizontal and vertical components of the resultant force. This complex calculation can be simplified by representing the...
1.9K
Respiratory System Abnormal Finding II: Palpation and Auscultation
1.3K
In assessing respiratory abnormalities, palpation and auscultation are critical tools for detecting and interpreting various pathophysiological changes. These techniques provide insight into underlying disorders by evaluating tactile sensations and sounds produced by the respiratory system.
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
1.3K


